The Thinker Guild had existed for over 100,000 years, from when Kryptonian civilization began to advance. Many noted scientists and scholars came from the guild and were instrumental in furthering Kryptonian technology and enabling them interstellar travel. Historically, the family most associated with the Thinker Guild was the House of El.
- Alura In-Ze
- Kara Zor-El
- Val-El - Krypton's foremost scientist (200 years before the planet's destruction)
- Jor-El - Krypton's foremost scientist (at the time of the planet's destruction)
- Lara Lor-Van